1566		Protestants destroy large parts of the Cathedral.
1581		The Iconoclasm hits the Cathedral again.
1585		Tranquillity returns with the restoration of Roman Catholic authority.

The fire of 1533 is not the only disaster by which the Cathedral was visited. Only 33 years later, during the Iconoclasm of August 20, 1566, Protestants destroyed a large part of the valuable interior. When Antwerp came under Protestant administration in 1581, a number of artistic treasures were once again destroyed, removed or sold. Only after 1585, with the restoration of Roman Catholic authority, did tranquility return once more.